Name | Biotin hydrazide |
Synonyms | 124278 Biotin-NHNH2 Biotin-Hydrazide BIOTIN-HYDRAZIDE BIOTIN HYDRAZIDE Biotin hydrazide D-Biotin Hydrazide (+)-BIOTIN HYDRAZIDE BIOTIN (LONG ARM) HYDRAZIDE 5-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanehydrazide 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanehydrazide 1H-thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aR,4S,6aR)- 1H-thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS,4S,6aR)- 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazid e, (3aS,4S,6aR)- 1H-Thieno(3,4-D)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3as-(3aalpha,4beta,6aalpha))- |
CAS | 66640-86-6 |
EINECS | 613-970-0 |
InChI | InChI=1/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1 |
InChIKey | KOZWHQPRAOJMBN-ZKWXMUAHSA-N |
Molecular Formula | C10H18N4O2S |
Molar Mass | 258.34 |
Density | 1.243±0.06 g/cm3(Predicted) |
Melting Point | 245-247°C |
Boling Point | 633.1±40.0 °C(Predicted) |
Flash Point | 336.7°C |
Solubility | DMSO: ≤20mg/mL |
Vapor Presure | 6.21E-16mmHg at 25°C |
Appearance | powder |
Color | White to Almost white |
BRN | 28347 |
pKa | 13.25±0.35(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Sensitive to heat |
Refractive Index | 1.553 |
MDL | MFCD00078532 |
In vitro study | Biotin Hydrazide is a biotinylation reagent used to biotinylate glycoproteins and glycolipids. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
HS Code | 29349990 |
Reference Show more | 1. Zhu, Chenggang, et al. "Developing an efficient and general strategy for immobilization of small molecules onto microarrays using isocyanate chemistry." Sensors 16.3 (2016): 378.https://doi.org/10.3390/s16030378 |
biological activity | Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, a carbonyl probe. |
Use | can be used for protein, antigen, antibody, nucleic acid (DNA, RNA) In affinity cytochemistry, the hydrazide functionalized group allows biotinylation of glycolipids and glycoproteins through the oligosaccharide moiety; Biotinylation of DNA, immobilization of DNA; |